FAQ Friday: Botox for Gastroparesis

Posted in: Treatment ♦ Friday, September 2nd, 2011, 2:20 pm ♦ 5 Comments

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5 Responses to “FAQ Friday: Botox for Gastroparesis”

  1. Posted by: Natasha
    September 3rd, 2011 at 12:10 am

    My gastroenterologist, on advice of Dr. Pasricha at Stanford, noted the 40-50% improvement rate in both Botox and saline groups and speculated that the injection itself may have some merit. By his suggestion, I received pyloric saline injection when I had my second upper endoscopy for stomach biopsy and, sure enough, it helped tremendously. My digestion speed didn’t change much, but the level of bloating and pain I had before and after the injection was like night and day — I’ve only had a handful of days since the injection (nearly 3 years ago) as bad as the 8 months beforehand. Whether this was an impressive placebo effect or a genuine result of the saline injection is impossible to say, but Dr. Pasricha was excited to hear my good results and indicated he wanted to continue exploring saline as a treatment in itself. For a condition as intractable as GP, a nearly 50% chance of improvement is huge.

  2. Posted by: Crystal
    September 3rd, 2011 at 5:27 pm

    Natasha, thanks for sharing. That’s so interesting! I’m going to ask my motility specialist about this next time I see him. (I agree with you: for me, a 50/50 chance is worth it!)

  3. Posted by: Natasha
    September 3rd, 2011 at 6:42 pm

    If I ever have another endoscopy, I’ll definitely ask my doctor to read about saline injection. Saline costs next to nothing and should be safe. Dr. Pasricha speculated a little about why saline might help — possibly some stimulant effect, possibly by washing away some accumulation or chemical we aren’t aware of as gastroparesis-related at this time, possibly due to the needle itself rather than the injected fluid (like some kind of internal acupuncture).

  4. Posted by: Sue
    September 10th, 2011 at 5:46 pm

    My son just had his 5th botox injection yesterday. He was diagnosed at 16 and will be 19 soon. The botox injection has been a miracle remedy for him. Prior to his doctor recommending this treatment he would vomit up to 20 times a day and was in severe pain. The botox relieves the symptoms almost completely and will last about 6 months. I just wish it worked as well for everyone because it really is a very easy procedure and the results are unbelievable.

  5. Posted by: Brittany Stickler
    July 3rd, 2014 at 2:29 pm

    I’m going for my first Botox injections next week! I’m a little, well, a lot nervous! I was diagnosed with GP 1 year ago and it has completely changed my health for the worse. I use to be a full time oncology nurse and had to give it up due to GP. There are no motility specialists in Idaho so I see a general GI doc to is so kind and caring! Wish me luck!

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